Nanosuspensions: a Strategy for Improved Bioavailability
نویسندگان
چکیده
Poor aqueous solubility of lead drug candidates remains an obstacle for drug development in pharmaceutical industries. Drugs with dissolution rate limited drug absorption show low bioavailability due to poor aqueous solubility of the drug. To overcome these problems different formulations of nanosized drugs were developed recently. Pharmaceutical nanosuspensions consist of dispersed solid drug particles in an aqueous vehicle with average particle sizes below 1μm. The present paper is a review of current development in nanosuspension formulation strategies for possible improvement in oral bioavailability.
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